The 8 Best Probiotics for Men, Approved by a Dietitian

Probiotics can be one of the most powerful and underrated tools in a man’s health regimen. You can lift, hydrate, and meal prep to your heart’s content, but as a dietitian, I’ve learned that if your gut’s not happy, your body won’t be either.

While most men turn to probiotics for digestion, these supplements can also contribute to a wide range of other wellness goals, from aiding a weakened immune system to offering urinary tract and prostate health support. Some strains may even aid nutrient absorption and mental well-being by supporting a balanced gut microbiome. 

But with so many probiotic supplements on the market, it can be tough to figure out which type is right for your health goals. I researched a variety of top-rated products across different formats to identify the best probiotic supplements for men in every category. While Live it Up is my top pick for gut health, I’m confident you’ll find the right probiotic for you.

Men’s Probiotic Supplements at a Glance

1. Live it Up Super Greens – Best Overall Men’s Supplement
2. MegaSporeBiotic – Best Spore-Based Probiotic
3. Culturelle Probiotic + Prebiotic – Best-Tasting Gummy
4. AG1 – Best Splurge for Athletes
5. Seed DS-01 Daily Synbiotic – Best for High Potency
6. Align Probiotic Bloating Relief and Food Digestion – Best for Sensitive Stomachs
7. Ritual Synbiotic+ – Best for Transparency and Traceability
8. Jarro-Dophilus EPS – Best Budget-Friendly Blend

Health Benefits of Probiotics for Men

Probiotics are healthy bacteria that offer several benefits and can be especially important for men’s health. Here are some top reasons men turn to probiotics, along with certain strains to look out for:

• Digestive Health: Probiotics help balance gut bacteria, digestion, and bloating.
  • Look for: Lactobacillus acidophilus, Bifidobacterium lactis, Bacillus coagulans.
• Healthy Immune System: A healthy gut supports a strong immune system, helping to fend off illness.
  • Look for: Lactobacillus rhamnosus, Bifidobacterium bifidum.
• Urinary and Prostate Health: Certain strains may help maintain urinary tract balance and support prostate health.
  •  Look for: Lactobacillus reuteri, Lactobacillus rhamnosus.
• Nutrient Absorption: Probiotics can improve the absorption of vitamins and minerals, which is important for energy levels and overall wellness.
  • Look for: Bifidobacterium longum, Lactobacillus plantarum.
• Mental Health: Emerging research links gut health to mood and cognitive function, making probiotics an ally in stress management.
  • Look for: Lactobacillus helveticus, Bifidobacterium infantis.

Top 8 Probiotics for Men of 2025

Maintaining a healthy gut microbiome plays a big role in overall health and wellness, and these top eight probiotic products stand out for men’s unique needs. Each product has a slightly different approach to supporting digestion, immunity, and more, so there’s something for everyone on this list.

1. Live it Up Super Greens: Best Overall Men’s Supplement

Live it Up Super Greens is a premium greens powder designed to support gut health, immunity, and daily energy levels. While it’s not solely a daily probiotic supplement, Live it Up includes 5 billion CFUs of dairy-free probiotics, digestive enzymes, and gut-supporting superfoods like ginger and peppermint, making it a well-rounded choice for men looking to support their digestive health from multiple angles.

• Digestive enzyme complex: Papain, bromelain, and vegetarian pepsin
• Dairy-free probiotics: Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium lactis
• Gut-supportive superfoods: Peppermint leaf, moringa, and ginger root
• Nutrients for men’s health: vitamin A, magnesium, and B vitamins

Price: A 30-serving pouch of Super Greens costs $59.99 ($1.99 per serving). Customers can subscribe and save 33% ($1.33 per serving).

Convenience and Flavor

Just one scoop mixes easily into water, smoothies, or milk alternatives (no blender required). Unlike many greens powders, Live it Up is never gritty or clumpy, making it a quick and enjoyable part of your daily routine. This super greens powder comes in two delicious flavors, naturally sweetened with monk fruit extract: Original (subtly minty and sweet) and Wild Berries (tart and fruity). 

Bottom Line

Live it Up Super Greens is a clean, great-tasting daily greens powder that supports gut health with a probiotic blend, enzymes, essential vitamins, and superfoods. It’s vegan, sugar-free, and third-party tested; ideal for men seeking a convenient, all-in-one supplement for digestion, immunity, and overall wellness. With a generous subscription discount and two flavorful options, it’s a standout pick in the gut health space.

2. MegaSporeBiotic: Best Spore-Based Probiotic

Created by Microbiome Labs, MegaSporeBiotic is a spore-based probiotic. This means the bacteria form a protective outer shell that helps them survive the acidic environment of the stomach and reach the intestines, where they can colonize the gut.

These shelf-stable capsules contain 4 billion CFUs from five Bacillus strains:

1. Bacillus indicus
2. Bacillus licheniformis
3. Bacillus clausii
4. Bacillus subtilis
5. Bacillus coagulans

Each one of the bacterial strains has a slightly different function. For example, Bacillus licheniformis produces proteases that aid protein digestion and synthesizes a full spectrum of B vitamins, while Bacillus clausii supports immune system function.

Price: A 30-serving container of MetaSporeBiotic costs $63.95 on Amazon ($2.13 per serving).

Convenience & Flavor

MegaSporeBiotic comes in capsule form with a serving size of two capsules per day, making it extremely convenient to take. The capsules are flavorless and easy to swallow.

Bottom Line

MegaSporeBiotic is a shelf-stable, spore-based probiotic that delivers five resilient Bacillus strains to support gut health, digestion, and immune function. It's vegan, allergen-friendly, and convenient to take, making it a smart pick for men looking for a simple, clinically grounded supplement. Some users may experience mild digestive side effects at first, and limited price transparency on the brand’s website may be a drawback for those wanting to purchase directly.

3. Culturelle Probiotic + Prebiotic: Best-Tasting Gummy

Culturelle’s Probiotic + Prebiotic dietary supplement is a berry-flavored gummy that supports digestion and immune health. Each serving contains:

• 1 g of fiber
• 1 g of sugar
• 30 mg of vitamin C
• 5 mg of sodium
• 2 g of inulin (a prebiotic)
• 2 billion CFUs of probiotics Bacillus subtilis and Bacillus coagulans

Bacillus subtilis supports gut barrier health and helps the immune system function properly, while Bacillus coagulans aids digestion and can help reduce occasional bloating and gas. For men who want a simple, tasty, and approachable way to support their gut and immune systems, without pills or powders, these gummies are a convenient option.

Price: A 26-serving bottle costs $15.99 ($0.61 per serving). Customers can subscribe and save 10% ($0.55 per serving).

Convenience & Flavor

These berry-flavored gummies are easy to take and taste great, making them a convenient option for those who prefer chewables over capsules. Most customers report enjoying the flavor, with only occasional complaints.

Bottom Line

Culturelle’s Probiotic + Prebiotic gummies are a convenient and tasty way to support gut and immune health, especially for those who dislike swallowing capsules. While the added sugar and shorter bottle life may be drawbacks for some, the product delivers solid value with a dual-action blend of prebiotics and probiotics in a vegan-friendly, shelf-stable format.

While 2 billion CFUs of probiotics per dose is relatively low compared to other products on this list, this may be an upside for some men, as a lower CFU count can be gentler on sensitive digestive systems. 

4. AG1: Best Splurge for Athletes

AG1 (formerly known as Athletic Greens) is a comprehensive greens powder designed to support digestion, immunity, energy, and more. Backed by clinical research and 83 ingredients, AG1 Next Gen combines superfoods, multivitamins, prebiotics, probiotics, and digestive enzymes into a single daily supplement. For men seeking an all-in-one supplement to support gut health, performance, and energy levels, AG1 offers a high-quality solution. 

For digestive health specifically, AG1 contains several standout ingredients:

• Ginger root to support gastric emptying and bloating relief
• Inulin, a prebiotic fiber that feeds good gut bacteria
• Bromelain, a digestive enzyme that helps break down protein
• 10 billion CFUs of dairy-free probiotics, including five clinically studied strains: Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus casei, and Lactobacillus plantarum

Price: AG1 costs $99 for a 30-serving pouch ($3.30 per serving). Customers can subscribe and save 20% ($2.65 per serving).

Convenience and Flavor

AG1 is easy to mix into water (one 13g scoop per 8–10 oz). The Original flavor has notes of pineapple and vanilla, while the new Tropical version is designed to taste like papaya and passionfruit. Some users report a strange and noticeable aftertaste from the stevia and some grittiness. 

Bottom Line

AG1 is a well-formulated, all-in-one supplement that includes gut-friendly ingredients like prebiotics, probiotics, digestive enzymes, and anti-inflammatory compounds. While it’s more expensive than many standalone probiotics—and may not suit those with sensitivities to soy, stevia, or high-FODMAP ingredients—it offers a convenient way to cover multiple wellness bases in one product.

It's worth noting that while AG1 Next Gen contains a wide range of functional ingredients, the large number of components means individual ingredient doses may be lower than in more targeted supplements. Additionally, the 10 billion CFUs of probiotics may not be ideal for those new to probiotics or prone to digestive sensitivity.

5. Seed DS-01 Daily Synbiotic: Best for High Potency

Seed DS-01 Daily Synbiotic is a high-quality daily supplement designed to support gut health, immune function, and whole-body health for adults 18+. Its unique capsule-in-capsule design helps protect the probiotics through digestion, ensuring more survive and reach the colon.

Formulated with 24 clinically studied probiotic strains, Seed is divided into functional blends targeting specific areas of health:

• Digestive health, gut immunity, and gut barrier integrity (37 billion AFU)
• Dermatological health (3.3 billion AFU)
• Cardiovascular health (5.25 billion AFU)
• Micronutrient synthesis (8.05 billion AFU)

Seed also includes prebiotics (organic rice fiber and rice extract blend) and 400 mg of microbiota-accessible polyphenolic compounds to help nourish beneficial bacteria.

For men, Seed offers a compelling option that goes beyond gut support; it may also benefit skin clarity and immune resilience, among other health benefits, making it a smart pick for those seeking more comprehensive wellness support.

Price: Seed costs $49.99 for a 30-day supply ($1.66 per serving), available only through a subscription.

Convenience and Flavor

Seed DS-01 comes in flavorless, easy-to-swallow capsules, with a recommended serving of two capsules per day. The brand's nested capsule design also eliminates the need for refrigeration, making it ideal for travel or daily routines.

Bottom Line

Seed DS-01 Daily Synbiotic is a rigorously formulated, multi-functional probiotic and prebiotic supplement that may appeal to men looking for a science-backed, whole-body approach to gut health. With 24 strains and targeted blends for digestion, immunity, skin, and more, it's a strong contender for those seeking more than just a basic probiotic. That said, its subscription-only model and higher price point may not be the right fit for every budget or need.

6. Align Probiotic Bloating Relief and Food Digestion: Best for Sensitive Stomachs

Align Probiotic Bloating Relief and Food Digestion is a once-daily supplement formulated to help alleviate occasional bloating, gas, and abdominal discomfort. Each capsule contains 1 billion CFUs of Bifidobacterium 35624™, a unique strain developed by gastroenterologists and backed by over 20 years of scientific research.

In addition to its gut-supportive probiotic, Align includes a digestive enzyme complex (alpha-amylase, neutral protease, lactase, cellulase, and lipase) to help break down carbohydrates, proteins, fats, and fibers. It also delivers 100% of the daily value of vitamin B12, which is an especially useful inclusion for vegan and vegetarian men, who are more likely to be deficient in this essential nutrient.

Price: Align costs $29.93 for a 28-day supply on Amazon ($1.07 per serving) and must be purchased through third-party retailers.

Convenience and Flavor

Align comes in capsule form, with a recommended serving of one capsule per day. The capsules are flavorless, easy to swallow, and do not require refrigeration.

Bottom Line

Align Probiotic Bloating Relief and Food Digestion offers a targeted, research-backed formula for men seeking relief from occasional bloating and gas. Its inclusion of digestive enzymes and vitamin B12 adds extra support for food breakdown and energy metabolism, particularly beneficial for plant-based eaters. While its probiotic dose is relatively low compared to other supplements in this list, the specific strain has been clinically shown to support digestive comfort. Just take note of the presence of common fillers and the lack of direct-to-consumer sales from the brand.

7. Ritual Synbiotic+: Best for Transparency and Traceability

Ritual Synbiotic+ is a three-in-one supplement that supports gut health by combining probiotics, prebiotics, and postbiotics into a single, shelf-stable capsule. Each serving delivers 11 billion CFUs from two clinically studied strains, Lactobacillus rhamnosus and Bifidobacterium animalis, both of which have been linked to digestive and immune support and can be particularly beneficial for men dealing with gut discomfort and irregularity. Lactobacillus rhamnosus is one of the most well-researched probiotic strains, with over 30 years of studies behind it.

This supplement also includes PreforPro, a patented prebiotic blend designed to help beneficial bacteria flourish in the gut. Some studies suggest PreforPro may help reduce inflammation more effectively than probiotics alone. 

Ritual is known for its transparency and commitment to quality. All products are third-party tested and formulated with input from a scientific advisory board made up of doctors, registered dietitians, and researchers.

Price: Ritual Synbiotic+ costs $60 for a 30-serving container ($2.00 per serving). Customers can subscribe and save 10% ($1.80 per serving).

Convenience and Flavor

Ritual Synbiotic+ comes in capsule form and is taken once daily, with or without food. The capsule is flavored with Ritual’s signature mint-scented tab, which gives it a distinct but polarizing scent. The supplement is easy to use and travel-friendly.

Bottom Line

Ritual Synbiotic+ is a high-quality, evidence-backed gut health supplement that blends probiotics, prebiotics, and postbiotics in a convenient, mint-scented capsule. For men seeking a simple, once-daily supplement to support digestion, immune function, and regularity, Ritual is a strong option. Its traceable ingredients and third-party testing make it well-suited for health-conscious men who value both transparency and performance, though the price point and inclusion of a few inactive ingredients may be drawbacks for some.

8. Jarro-Dophilus EPS – Best Budget-Friendly Blend

Jarro-Dophilus EPS is a gut health supplement from Jarrow Formulas formulated with eight probiotic strains to support digestive and immune health. Each capsule delivers 10 billion CFUs from a diverse blend of clinically studied probiotics, including:

1. Lacticaseibacillus rhamnosus
2. Lactobacillus helveticus
3. Pediococcus acidilactici
4. Lacticaseibacillus casei
5. Bifidobacterium longum
6. Lactiplantibacillus plantarum
7. Bifidobacterium breve
8. Lactococcus lactis

The formula includes an enteric coating that helps probiotics survive stomach acid and reach the intestines—an essential feature for maximizing potency and effectiveness.

Price: A 30-day supply of Jarro-Dophilus EPS costs $21.99 on Amazon ($0.73 per serving), and is only available through third-party retailers.

Convenience and Flavor

Adults are advised to take two capsules once daily with water or juice, preferably on an empty stomach. The capsules are unflavored, easy to swallow, and shelf-stable, making them a good option for travel or daily routines.

Bottom Line

Jarro-Dophilus EPS is a straightforward, probiotic-only supplement that offers eight diverse strains in a shelf-stable, travel-friendly format. It’s an affordable choice for men seeking basic gut and immune support without added prebiotics or enzymes. However, the presence of allergens and fillers, as well as limited availability through the brand’s site, may be drawbacks for some.

How to Take Probiotics

Probiotics come in several forms, each with unique perks and potential downsides. Choosing the right type depends on your lifestyle, convenience, and personal preferences.

Capsules

Capsules are one of the most popular forms of probiotics. Many are shelf-stable, but some require refrigeration to keep the probiotics alive. They’re easy to take but can sometimes cause digestive discomfort if the probiotic dosage is high or if you have a sensitive stomach. 

Whether you're prone to digestive issues or considering a particularly potent supplement, check the CFU (colony-forming unit) count on the product’s label. Most probiotics contain between 1 and 10 billion CFUs per serving, but some go much higher, which may affect how your body responds.

Powder

Powders like Live it Up Super Greens and AG1 offer a flexible way to get your probiotics along with other gut-supporting nutrients like digestive enzymes and superfoods. Powders are easy to mix into water, smoothies, and milk and also avoid the fillers found in some capsules and gummies. They’re great for those who want a customizable daily routine and don’t like swallowing pills.

Gummies

Gummies make probiotic supplements taste like candy, which can make taking them more enjoyable, especially if you dislike capsules or powders. They often include prebiotics, but keep in mind some contain added sugars and gels. 

Drinks

Probiotic drinks combine hydration with live bacteria. Kombucha, kefir, and even probiotic sodas can be an easy way to support gut health on the go. They often contain added sugars, caffeine, or flavors, so be mindful of ingredient lists.

Try Live it Up Super Greens for Probiotic Support

From high-potency capsules to tasty gummies and all-in-one powders, there’s no shortage of probiotic supplements tailored to support men’s health. While each product on this list has its strengths, Live it Up stands out as a versatile option that can meet a range of wellness goals in addition to digestion.

It delivers 5 billion CFUs from four clinically backed probiotic strains, along with a robust digestive enzyme blend, gut-supporting superfoods, and naturally occurring nutrients, all in a great-tasting, easy-to-mix powder. It’s allergen-friendly, third-party tested for quality and safety, and free of fillers, added sugars, and artificial ingredients at an accessible price point.

Of course, no supplement is one-size-fits-all. But as a registered dietitian, Live it Up Super Greens is a product I feel confident recommending to men looking for comprehensive digestive balance, immune system support, and enhanced energy levels. It’s a well-rounded, thoughtfully formulated choice for building a consistent gut health routine.

Frequently Asked Questions about Probiotics for Men

Still have questions? Here are answers to our most asked questions about probiotics for men. 

Are probiotics good for you?

Yes, probiotics can support digestive health, nutrient absorption, and the immune system. Certain strains may also help with mental health, urinary infections, healthy metabolism, and support prostate health in men. Like any supplement, effectiveness depends on the specific strains used and your individual needs. Talk to a healthcare professional before starting a new probiotic routine.

What are signs probiotics are working?

You may notice more regular bowel movements, less bloating or gas, and improved digestion after regularly taking a probiotic. Some people also experience better energy levels or mood. These beneficial effects can take a few days to several weeks, depending on your gut health and the type  of probiotic strain and quantity. Subtle improvements are usually a good sign it's working. If you are seeking help for a more severe GI disorder, it's best to seek out a healthcare professional.

Can you take too many probiotics?

Yes, taking too many probiotics may lead to side effects like gas, bloating, or upset stomach, especially if your body isn’t used to them. It’s best to start with a moderate dose and increase slowly if needed. More isn’t always better, and the right strain and amount matter more than sheer quantity.

What’s the best time to take probiotics?

The best time to take probiotics depends on the type and your routine. Many strains survive better when taken with food, especially meals containing fat, carbs, and protein. Morning is a good time since your digestive system is active, but ultimately, the key is consistency. Take them when you’re most likely to remember.

What should you not mix with probiotics?

To get the most out of probiotics, it’s best to avoid mixing them with acidic foods and drinks like coffee, citrus juice, or tomato sauce, which may affect bacterial survival. Ultra-processed foods, sugary sodas, and refined oils can also disrupt gut balance. For optimal results, pair probiotics with a balanced, pH-neutral meal.

References

• https://www.nccih.nih.gov/health/probiotics-usefulness-and-safety 
• https://pubmed.ncbi.nlm.nih.gov/32992898/ 
• https://www.hopkinsmedicine.org/health/wellness-and-prevention/digestive-enzymes-and-digestive-enzyme-supplements 
• https://www.healthline.com/nutrition/peppermint-tea 
• https://www.hopkinsmedicine.org/health/wellness-and-prevention/ginger-benefits 
• https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/bacillus-subtilis 
• https://www.healthline.com/health/bacillus-coagulans 
• https://culturelle.com/products/probiotic-adult-daily-gummies 
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341159/ 
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463098/ 
• https://www.mdpi.com/2072-6643/16/13/2060 
• https://www.nccih.nih.gov/health/probiotics-usefulness-and-safety 
• https://pubmed.ncbi.nlm.nih.gov/30741841/ 
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• https://health.clevelandclinic.org/best-time-to-take-probiotics 
• https://wellgard.co.uk/blogs/health-insiders/what-foods-to-avoid-while-taking-probiotics